PDHA1 purified MaxPab mouse polyclonal antibody (B01P)
产品名称： PDHA1 purified MaxPab mouse polyclonal antibody (B01P)
英文名称： PDHA1 purified MaxPab mouse polyclonal antibody (B01P)
产品编号： H00005160-B01P
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse polyclonal antibody raised against a full-length human PDHA1 protein.
- Immunogen:
- PDHA1 (AAH02406, 1 a.a. ~ 390 a.a) full-length human protein.
- Sequence:
- MRKMLAAVSRVLSGASQKPASRVLVASRNFANDATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFCHLCDGQEACCVGLEAGINPTDHLITAYRAHGFTFTRGLSVREILAELTGRKGGCAKGKGGSMHMYAKNFYGGNGIVGAQVPLGAGIALACKYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKLPCIFICENNRYGMGTSVERAAASTDYYKRGDFIPGLRVDGMDILCVREATRFAAAYCRSGKGPILMELQTYRYHGHSMSDPGVSYRTREEIQEVRSKSDPIMLLKDRMVNSNLASVEELKEIDVEVRKEIEDAAQFATADPEPPLEELGYHIYSSDPPFEVRGANQWIKFKSVS
- Host:
- Mouse
- Reactivity:
- Human
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody reactive against mammalian transfected lysate.
- MSDS:
Download
- Applications
- Western Blot (Tissue lysate)
- PDHA1 MaxPab polyclonal antibody. Western Blot analysis of PDHA1 expression in human liver.
- Protocol Download
- Western Blot (Cell lysate)
- PDHA1 MaxPab polyclonal antibody. Western Blot analysis of PDHA1 expression in HepG2.
- Protocol Download
- Western Blot (Transfected lysate)
- Western Blot analysis of PDHA1 expression in transfected 293T cell line (H00005160-T01) by PDHA1 MaxPab polyclonal antibody.
Lane 1: PDHA1 transfected lysate(43.01 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
enlarge this image- Immunoperoxidase of purified MaxPab antibody to PDHA1 on formalin-fixed paraffin-embedded human stomach. [antibody concentration 1.5 ug/ml]
- Protocol Download
- Entrez GeneID:
- 5160
- GeneBank Accession#:
- BC002406
- Protein Accession#:
- AAH02406
- Gene Name:
- PDHA1
- Gene Alias:
- PDHA,PDHCE1A,PHE1A
- Gene Description:
- pyruvate dehydrogenase (lipoamide) alpha 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The pyruvate dehydrogenase complex is a nuclear-encoded mitochondrial matrix multienzyme complex that provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle by catalyzing the irreversible conversion of pyruvate into acetyl-CoA. The PDH complex is composed of multiple copies of 3 enzymes: E1 (PDHA1); dihydrolipoyl transacetylase (DLAT; MIM 608770) (E2; EC 2.3.1.12); and dihydrolipoyl dehydrogenase (DLD; MIM 238331) (E3; EC 1.8.1.4). The E1 enzyme is a heterotetramer of 2 alpha and 2 beta subunits. The E1-alpha subunit contains the E1 active site and plays a key role in the function of the PDH complex (Brown et al., 1994 [PubMed 7853374]).[supplied by OMIM
- Other Designations:
- OTTHUMP00000023015,pyruvate dehydrogenase E1 alpha subunit
- Gene Pathway
- Biosynthesis of alkaloids derived from histidine and purine
- Biosynthesis of alkaloids derived from ornithine, lysine and nicotinic acid
- Biosynthesis of alkaloids derived from shikimate pathway
- Biosynthesis of alkaloids derived from terpenoid and polyketide
- Biosynthesis of phenylpropanoids
- Biosynthesis of plant hormones
- Biosynthesis of terpenoids and steroids
- Butanoate metabolism
- Citrate cycle (TCA cycle)
- Glycolysis / Gluconeogenesis
- Metabolic pathways
- Pyruvate metabolism
- Valine, leucine and isoleucine biosynthesis